Since the beginning of the EuroPMP COST Action about 1.5 years ago, the Action has included researchers from many countries, not just in Europe, but around the world. The number of countries now taking part in the action has doubled in the past year alone, and now includes partners from over 23 countries including Azerbaijan, Bosnia and Herzegovina, Belgium, Germany, Greece, Spain, Finland, France, Croatia, North Macedonia, Ireland, Israel, Italy, Latvia, Montenegro, Norway, Pakistan, Poland, Portugal, Romania, Sweden, Turkey and the United Kingdom. The EuroPMP COST Action aims to increase cooperation between researchers across Europe and around the world to improve research into the cause, detection and treatment of Pseudomyxoma…
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Rescheduling of the PMP Workshop
Save the date! In light of the continuing issues around the COVID-19 pandemic, it has not been possible to reschedule the Pathology Workshop for the near future. Therefore, the Core Committee has proposed a new date of the 10-11th December 2020 for the PMP Pathology Workshop in Basingstoke. As before, the Core Committee will send information to all EuroPMP members closer to the date. If the COVID-19 pandemic has not resolved by this time, the Core Committee may need to reschedule to an even later date. We remain hopeful, however, that the medical emergency will have subsided by December, and so we ask all pathology-interested members to block the time…
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NORD ACPMP Award for Flatmark Lab
Prof Kjersti Flatmark’s research group in Oslo have been awarded a NORD ACPMP Research Grant (ID: 19010) to look into the identification of biomarkers in the blood stream of patients. The title of the study is “ctDNA for monitoring patients with pseudomyxoma peritonei”. Pseudomyxoma peritonei (PMP) is a rare abdominal cancer that exhibits specific DNA mutations. After treatment by surgery and intraperitoneal chemotherapy, radiological follow-up has low sensitivity and specificity for detecting disease recurrence. Mutations may be detectible in blood samples, and in this project we will establish and test a method for analyzing circulating tumor DNA (ctDNA) from patients with PMP before and after surgery. If successful, this method…
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New STSM to Oslo
Yaroslaw Sautkin, a EuroPMP member from Germany, has completed a Short-Term Scientific Mission to Professor Kjersti Flatmark’s Translational Cancer Therapy lab at Oslo University Hospital’s Institute for Cancer Research. While on his STSM, Yaroslaw learned more about the use of experimental animal models for pseudomyxoma peritonei (PMP) in order to further the work that his own institution, the University of Tübingen, is undertaking into the use of PIPAC with mucolytic substances. Yaroslaw’s visit allowed members of both teams to meet and share knowledge, leading to stronger synergies between their researchers. Both groups are now looking forward to working on research projects together in the future. STSMs are offered several times…
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Informacije za ljekare
Pseudomyxoma peritonei (PMP) je rjetko oboljenje sa incidencom od oko 3,2:1 000 000. To je dijagnoza koju ljekar može postaviti jednom do dva puta ili čak ili nijednom u toku čitavog radnog vijeka. Obično je teško napraviti diferencijaciju između PMP i drugih mnogo učestalijih tipova mucinoznih tumora, kao što je karcinom ovarija, bez temeljite patohistološke evaluacije iskusnog patologa. To je dijagnoza koju ljekar može postaviti jednom do dva puta ili čak nijednom u toku čitavog radnog vijeka. Obično je teško napraviti diferencijaciju između PMP i drugih, mnogo učestalijih tipova mucinoznih tumora, kao što je karcinom ovarija, bez temeljite patohistološke evaluacije iskusnog patologa. Pseudomyxoma je opsežno diseminirana mucinozna neoplazma koja se…
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COST Annual General Meeting and Pathology Workshop
The annual Management Committee and Working Group meeting of the EuroPMP COST Action will take place on the 13th March 2020 in Basingstoke, U.K. A pathology workshop will be held the day before the AGM (12th March), looking into the most recent advances in the field of PMP pathology with speakers from around the world set to take the podium. A draft programme is available here. The meeting and the associated workshop will be held at the Ark Conference Centre, Basingstoke and North Hampshire Hospital, Basingstoke, U.K. The registration form may be accessed here.
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STSM Call for Applications – Spring 2020
Short Term Scientific Missions (STSM) are exchange visits between researchers involved in a COST Action, allowing scientists to visit an institution or laboratory in another COST Member state. STSMs are institutional visits aimed at supporting individual mobility, fostering collaboration between individuals. These scientific missions may last from 5 days to up to 6 months. Their aim is to promote collaboration in excellent research infrastructures and share new techniques that may not be available in a participant’s home institution or laboratory. The deadline for the call is 29 February 2020. The STSM itself must take place prior to the end of April 2020. For more information about applying for an STSM,…
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Intraperitoneal Mitomycin C Improves Survival in PMP
EuroPMP’s own Professor Kjersti Flatmark and colleagues have published new findings showing that the use of mitomycin C with intraperitoneal chemotherapy (IPEC) during cytoreductive surgery doubled survival times and reduced tumour growth in a xenograft model when compared to surgery alone. In a signet ring cell model of high-grade PMP, three different methods were tested: normal cytoreductive surgery (CRS), CRS and intraperitoneal chemotherapy of normal temperature and CRS with hyperthermic IPEC (HIPEC). After examination of the methods, it was found that tumour weights were noticeably lower in the groups receiving either IPEC or HIPEC when compared to cytoreductive surgery alone. While more testing will be needed to confirm this finding…
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EuroPMP ECI Workshop in Cordoba
The EuroPMP COST Action held a workshop for its Early Career Investigator members in Cordoba on Friday, 4th October. In attendance were members from across Europe, including Spain, Italy, Norway, the United Kingdom, Germany and France. Many interesting talks were given on subjects ranging from the diagnosis and treatment of PMP to novel research going on in the field. Session 1 saw talks by Dr Norman Carr (UK) and Dr Martin (Spain) around the pathology and radiology of PMP. Much work is ongoing around diagnostic techniques and classifications, including the standardisation of methods in these two diverse fields. Dr Andrew Thrower (UK) gave an informative presentation on the evaluation…
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Places Still Available for the ECI Workshop!
The Early Career Investigator PMP Workshop in Cordoba is only a few weeks away, but we still have available places to attend the event. If you are interested in attending the workshop, you can click this link to sign up. The programme can be viewed here. See you there!
