Prof Kjersti Flatmark’s research group in Oslo have been awarded a NORD ACPMP Research Grant (ID: 19010) to look into the identification of biomarkers in the blood stream of patients. The title of the study is “ctDNA for monitoring patients with pseudomyxoma peritonei”.
Pseudomyxoma peritonei (PMP) is a rare abdominal cancer that exhibits specific DNA mutations. After treatment by surgery and intraperitoneal chemotherapy, radiological follow-up has low sensitivity and specificity for detecting disease recurrence. Mutations may be detectible in blood samples, and in this project we will establish and test a method for analyzing circulating tumor DNA (ctDNA) from patients with PMP before and after surgery. If successful, this method may represent a minimally invasive, fast and reliable method for follow-up of PMP patients.
Congratulations to Professor Flatmark and her PMP research team members, Dr Annette Torgunrud, Dr Karianne Giller Fleten and Dr Christin Lund-Andersen.